| Table 3. Effect of Cleistanthus collinus on serum LH, FSH and testosterone levels of Wistar rats. | ||||
| Control (saline) | Cyclophosphamide 100 mg/kg | C. collinus 200 mg/kg | C. collinus 400 mg/kg | |
|---|---|---|---|---|
| LH (mIU/L) | 13.8 (11.5-19.5) | 3.8 (3.5-5.6)c | 11.95 (9.2-13.7)e | 8.3 (7.2-10.6)a,d |
| FSH (mIU/L) | 14.68±4.04 | 13.56±2.40 | 14.41±1.99 | 10.30±2.33a |
| Testosterone (nmole/L) | 34.0±6.20 | 19.2±3.90b | 28.9±7.60 | 25.70±3.59a |
Rats received saline or plant extract through oral gavage daily for 28 days. Cyclophosphamide was given through intraperitoneal route once in a week for four weeks. The following day, the animals were slaughtered, and the parameters were assessed. Data are represented as mean ± SD or median (IQR), n=6. ap<0.05, bp<0.01, cp<0.001 compared to the control group; dp<0.05, ep<0.01 compared to the cyclophosphamide group. The parametric test used was the one-way ANOVA with the Tukey Krammer post hoc test; and the Non-parametric test used was the Kruskal Wallis with Dunn’s multiple comparison post hoc test, based on the normality testing.