| Table 4. Effects of Cleistanthus collinus on tissue MDA, catalase and GSH levels of Wistar rats. | ||||
| Control (saline) | Cyclophosphamide 100 mg/kg | C. collinus 200 mg/kg | C. collinus 400 mg/kg | |
|---|---|---|---|---|
| MDA nmole/ml | 3.24±1.22 | 7.24±1.10c | 4.41±2.19e | 6.78±1.13b |
| Catalase K/ml | 2.63±0.83 | 0.86±0.61c | 1.68±0.22d | 1.33±0.45e |
| GSH µg/mg of protein | 94.30±7.18 | 47.53±10.34c | 62.66 ±1.75c,e | 60.71±6.43c,d |
Rats received saline or plant extract through oral gavage daily for 28 days. Cyclophosphamide was given through intraperitoneal route once in a week for four weeks. The following day, the animals were slaughtered, and the parameters were assessed. Data are expressed as mean ± SD, n=6. ap<0.05, bp<0.01, cp<0.001 compared with the control group. dp<0.05, ep<0.01 compared with the cyclophosphamide group.