| Table 4. Main relationships of male age with sperm parameters. | |
| Higher male age | Higher male age |
|---|---|
| Correlations with: | No correlations with: |
| Excessive ROS production | DNA fragmentation |
| Increased DNA fragmentation | Immature chromatin |
| Increased DNA methylation | Sperm concentration |
| Increased sperm aneuploidies | Sperm motility |
| Sperm vacuoles | Sperm morphology |
| Decreased sperm concentration | |
| Decreased sperm motility | Differences may be due to: |
| Decreased sperm morphology | Sperm selection in ICSI |
| Female age bias | |