| Table 2. miR-181d-5p predicts hyper response to COS independently of age and FSH levels. Binary logistic regression was applied to evaluate the influence of miR-181d-5p levels on prediction of COS response. | |||||||
| Groups | Variable | p-value | Exp(B) | Sens. | Spec. | PPV | NPV |
|---|---|---|---|---|---|---|---|
| PR vs. HR | miR-181d-5p | 0.008 | 2.351 | 55.0% | 84.0% | 73.3% | 70.0% |
| age | 0.275 | (n.p.) | |||||
| FSH | 0.929 | (n.p.) | |||||
| NR vs. HR | miR-181d-5p | 0.006 | 2.483 | 42.1% | 86.2% | 66.7% | 69.4% |
| age | 0.062 | (n.p.) | |||||
| FSH | 0.147 | (n.p.) | |||||
| PR vs. NR | miR-181d-5p | 0.267 | (n.p.) | n.a. | n.a. | n.a. | n.a. |
| age | 0.392 | (n.p.) | |||||
| FSH | 0.155 | (n.p.) | |||||
n.p., not present in equation; n.a., not applicable; Sens., sensitivity; Spec., specificity; PPV, positive predictive value; NPV, negative predictive value; FSH, follicle-stimulating hormone.