| Table 2. Clinical outcomes in the GnRH antagonist protocol (group 1) versus long GnRH agonist protocol with corifollitropin alfa followed by hMG - simplified long protocol (group 2). | |||
| Group 1 GnRH antagonist |
Group 2 Simplified long protocol |
p-value | |
|---|---|---|---|
| Interval between first and second cycle, days (SD) | 312 (137) | 289 (149) | 0.355 |
| Days of stimulation, median (IQR) | 9 (8-10) | 12 (11-13) | <0.001 |
| Number of oocytes retrieved, median (IQR) | 7 (5-11.75) | 7 (5-10) | 0.802 |
| Number of metaphase II oocytes, median (IQR) | 4.5 (3-7) | 4 (3-7) | 0.915 |
| Embryos obtained, median (IQR) | 1 (0-2) | 1 (0-2) | 0.884 |
| Cycle cancellation, n (%) | 2 (2.3) | 1 (1.5) | 1.000 |
| Embryo transfer, n (%) | 53 (60.2) | 37 (56.1) | 0.604 |
| Embryos cryopreserved, median (min-max) | 0 (0-7) | 0 (0-6) | 0.458 |
| Positive hCG per cycle, n (%) | 21 (23.9) | 13 (19.7) | 0.537 |
| Clinical pregnancy per cycle, n (%) | 17 (19.3) | 12 (18.2) | 0.858 |
| Clinical pregnancy per transfer, n (%) | 17 (29.8) | 15 (35.7) | 0.536 |
| Live birth per cycle, n (%) | 16 (18.2) | 10 (15.2) | 0.619 |