| Table 3. Clinical characteristics, hormonal profile and reproductive outcomes of normoovulatory infertile women according to rs2153157:G>A variant of the SYCP2L gene. | ||||
| Variables | Genotypes SYCP2L rs2153157:G>A |
p-value | ||
|---|---|---|---|---|
| GG | GA | AA | ||
| N | 0 | 49 | 100 | - |
| Age (years) | - | 32 (31-33) | 33 (32-34) | 0.39a |
| BMI (kg/m2) | - | 23.9 (22.5-24.9) | 24.0 (23.3-24.8) | 0.54a |
| Menarche (years old) | - | 13.0 (12.0-13.0) | 13.0 (12.0-13.0) | 0.98a |
| Menstrual cycle interval (days) | - | 28 (28-30) | 28 (28-29) | 0.40a |
| Infertility duration (years) | - | 3.0 (2.1-4.0) | 3.0 (3.0-4.0) | 0.15a |
| FSH (UI/mL) | - | 6.1 (5.7-6.7) | 6.1 (5.7-6.6) | 0.72a |
| LH (UI/mL) | - | 3.2 (2.6-3.5) | 2.8 (2.7-3.2) | 0.30a |
| Progesterone (ng/mL) | - | 4.1 (1.2-11.0) | 8.2 (5.6-11.0) | 0.53a |
| Prolactin (ng/mL) | - | 15.0 (14.0-19.4) | 16.0 (13.0-17.7) | 0.33a |
| AMH (ng/mL) | - | 3.7 (3.2-5.8) | 2.9 (2.4-3.6) | 0.01a |
| AFC | - | 9 (8-10) | 9 (8-11) | 0.47a |
| COS protocol (n, %) 100 UI 150 UI 200 UI |
- - - |
26 (53.1%) 4 (8.2%) 19 (39.8%) |
47 (47.0%) 13 (13.0%) 40 (40.0%) |
0.63b |
| Response to COS (n, %) Poor Satisfactory Hyper-response |
- - - |
13 (26.5%) 27 (55.1%) 9 (18.4%) |
19 (19.0%) 70 (70.0%) 11 (11.0%) |
0.19b |
| Oocytes retrieved | - | 6 (4-7) | 6 (5-7) | 0.48a |
| MII Oocytes | - | 5.0 (3.0-6.9) | 5.0 (4.0-6.0) | 0.39a |
| Embryos | - | 3 (2-4) | 3 (2-4) | 0.55a |
| Pregnancy rate (n, %) | - | 17 (34.7%) | 29 (29.0%) | 0.48b |
The variables were shown as median and CI (95%): 95% Confidence Interval; BMI: body mass index; COH: controlled ovarian hyperstimulation; FSH: follicle stimulating hormone;
LH: luteinizing hormone; AMH: anti-Müllerian hormone; AFC: antral follicle counting; MII: oocytes metaphasis II.a Mann-Whitney Test and b Chi-squared test.