| Table 4. Comparison of study design, sample size, triggers and ART procedure in different studies. | |||||||
| Author | Study Design | Participants | Trigger | ART | |||
|---|---|---|---|---|---|---|---|
| Total | Group | Group | |||||
| Intervention | Reference | Intervention | Reference | ||||
|
|
Prospective RCT |
221 | 105 | 106 | Triptorelin 0.2mg + hCG 5,000IU |
hCG 5,000IU | IVF and IVF-ICSI |
|
|
Retrospective Cohort Study |
376 (378 cycles) |
191 | 187 | Triptorelin 0.2mg + rhCG 250μg |
rhCG 250μg | IVF and IVF-ICSI |
|
|
Prospective RCT |
120 | 61 | 59 | Triptorelin 0.2mg + hCG 5,000IU |
hCG 5,000IU | IVF-ICSI |
|
|
Prospective RCT |
76 | 38 | 38 | Leuprolide 1mg + hCG 5,000IU |
hCG 10,000IU | IVF-ICSI |
|
|
Retrospective Case Control |
156 | 84 | 72 | Leuprolide 0.5mg + rhCG 250μg |
rhCG 250μg | IVF and IVF-ICSI |
|
|
Prospective RCT |
126 | 63 | 63 | Triptorelin 0.2mg + hCG 5,000IU |
hCG 10,000IU | ICSI |
|
|
Prospective RCT |
160 | 80 | 80 | Leuprolide 1mg + rhCG 250μg |
rhCG 250μg | ICSI |
| Haas et al., 2020 | Prospective RCT |
155 | 77 | 78 | Buserelin 0.5mg + 10,000IU hCG |
hCG 10,000IU + Placebo (normal saline) |
IVF and IVF-ICSI |
| Current study | Prospective RCT |
100 | 50 | 50 | Leuprolide 1mg + rhCG 250μg |
rhCG 250μg | IVF and IVF-ICSI |