Table 1. Main findings in semen parameters reported in the included studies.
Study Semen volume Sperm concentration Sperm motility Sperm morphology
Apaydin et al., 2022 No alterations were found. Reduced in three of seven patients. Progressive motility reduced in three of seven patients. Not evaluated
Best et al., 2021 No alterations were found. Reduced in patients with COVID-19 compared to controls. Not evaluated Not evaluated
Donders et al., 2022 No alterations were found

Reduced in 25% of patients.

Great decrease relative to early infection.

Reduced in 44% of patients. Great reduction relative to early and severe infection. Reduced in 67% of patients.
Great reduction depending on severity of disease.
Erbay et al., 2021 Reduced when compared to same patients before moderate COVID-19 Reduced when compared to same patients before moderate COVID-19. Reduced when compared to same patients before moderate COVID-19. Not evaluated.
Guo et al., 2021 No alterations were found. No alterations were found. Reduced when compared to controls. No alterations were found.
Holtmann et al., 2020 No alterations were found Reduced in group of patients with moderate infection compared to those with mild infection and controls. Reduced in group of patients with moderate infection compared to those with mild infection and controls. Not evaluated.
Koç & Keseroglu, 2021 Reduced when compared to same patients before COVID-19. No alterations were found. Reduced when compared to same patients before COVID-19. Reduced when compared to same patients before COVID-19.
Li et al., 2020b Not evaluated. Reduced in patient with
COVID-19 compared to controls.
Not evaluated. Not evaluated.
Hajizadeh Maleki & Tartibian, 2021 Reduced in patients with COVID-19 compared to controls.
No change after disease recovery.
Reduced in patient with
COVID-19 compared to controls.
Increased after 60 days of recovery.
Reduced in patient with COVID-19 compared to controls. Increased after 60 days recovery. Reduced in patient with COVID-19 compared to controls.
No change after disease recovery.
Rafiee & Bagher Tabei, 2021 Reduced immediately after COVID-19. Reduced immediately after COVID-19. Reduced immediately after COVID-19. Reduced immediately after COVID-19.
Ruan et al., 2021 Within WHO lower limits. Within WHO lower limits. Within WHO lower limits. Within WHO lower limits.
Seckin et al., 2022 No alterations were found. No alterations were found. Patient with 0% motility in the first evaluation after COVID-19 and improvement after three months of recovery, reaching 72.5% progressive motility. Patient demonstrated 9% of normal morphology after three months recovery.
Temiz et al., 2021 No alterations were found. No alterations were found. No alterations were found. Significantly altered in patients with COVID-19 compared to controls.