Table 1. Main characteristics of infertile women, according to their FSHR gene Ala307Thr (rs6165) genotype.
Characteristics FSHR Ala307Thr Genotype p
Total Thr/Thr Thr/Ala Ala/Ala
n (%) 450 (100%) 141 (31.3%) 213 (47.4%) 96 (21.3%)
Age (years) 34.6±4.2 35.0±3.8 34.5±4.1 34.5±4.7 0.57
BMI (kg/m2) 24.3±4.2 24.3±4.0 24.3±4.0 24.4±4.7 0.81
AMH(ng/ml) 1.8±2.2 1.7±2.3 1.9±2.1 1.6±2.1 0.26
AFC (n) 13.0±8.2 12.6±8.7 13.4±7.4 12.3±9.0 0.11
ORPI* 1.1±2.8 1.1±3.4 1.1±1.8 1.2±3.4 0.16
Infertility (%) 0.91
1a 76.9%(346/450) 78.0%(110/141) 76.5%(163/213) 76.0%(73/96)
2a 23.1%(104/450) 22.0%(31/141) 23.5%(50/213) 24.0%(23/96)
Time of infertility (years) 4.2±3.3 4.4±3.6 4.0±3.2 4.3±3.0 0.24
Etiology (%) 0.30
Male 36.4% (164/450) 36.2%(51/141) 39.0%(83/213) 31.2%(30/96)
Idiopathic 31.4% (141/450) 30.5%(43/141) 29.6%(63/213) 36.5%(35/96)
Endometriosis 14.9% (67/450) 19.2%(27/141) 13.6%(29/213) 11.5%(11/96)
Tuboperitoneal 10.3% (46/450) 7.8%(11/141) 11.7%(25/213) 10.4%(10/96)
Male+endometriosis 3.3% (15/450) 2.8%(4/141) 3.3%(7/213) 4.2%(4/96)
Male+tuboperitoneal 2.2% (10/450) 2.1%(3/141) 1.0%(2/213) 5.2%(5/96)
endometriosis+ tuboperitoneal 1.1% (5/450) 0.7%(1/141) 1.9%(4/213) 0
Male+endometriosis+ tuboperitoneal 0.4% (2/450) 0.7%(1/141) 0 1.0%(1/96)

* ORPI: [AMH(ng/ml) × AFC (n/2-9mm)]/age (years).