Table 3. Clinical outcomes of the study population according to FSHR gene Ala307Thr (rs6165) genotype.
Clinical outcomes FSHR Ala307Thr Genotype p
Total Thr/Thr Thr/Ala Ala/Ala
Fertilization rate (%) 64.5±27.0% 64.5±26.4 64.6±26.5% 64.4±29.9% 0.96
Fertilization fail (%) 5.3% (24/450) 5.7%(8/141) 3.8%(8/213) 8.3%(8/96) 0.23
Freeze all (%) 1.8% (8/450) 0 2.8% (6/213) 2.1%(2/96) 0.11
Embryo transfers (n) (μ±SD) 1.9±0.6 1.9±0.5 1.9±0.7 2.1±0.8 0.24
implantation rate (fresh cycle) (%) 25.3%(200/789) 23.9%(58/243) 26.1%(97/371) 25.7%(45/175) 0.82
implantation rate (frozen cycle) (%) 20.5%(54/264) 20.2%(19/94) 21.9%(30/137) 15.2%(5/33) 0.73
Cumulative implantation rate (%) 24.1%(254/1053) 22.8%(77/337) 25.0%(127/508) 24.0%(50/208) 0.78
Pregnancy rate, patient (%)
Fresh cycle 33.8% (152/450) 31.2% (44/141) 35.2%(75/213) 34.4% (33/96) 0.79
Cumulative(fresh cycle + frozen cycle) 44.0% (198/450) 43.3% (61/141) 46.5%(99/213) 39.6% (38/96) 0.56
Pregnancy, transfer (%)
Fresh cycle 38.2%(152/398) 34.6%(44/127) 39.9%(75/188) 39.8%(33/83) 0.65
Cumulative(fresh cycle + frozen cycle) 36.7%(198/539) 34.5%(61/177) 38.1%(99/260) 37.3%(38/102) 0.77
Miscarriage rate (%)
Fresh cycle 18.4%(28/152) 13.6%(6/44) 22.7%(17/75) 15.2%(5/33) 0.42
Cumulative(fresh cycle+frozen cycle) 19.7%(39/198) 11.5%(7/61) 25.2%(25/99) 18.4%(7/38) 0.22
Cumulative live births, patient (%)
Fresh cycle 27.6% (124/450) 27.0% (38/141) 27.2%(58/213) 29.2% (28/96) 0.79
Cumulative(fresh cycle+frozen cycle) 35.3% (159/450) 38.3% (54/141) 34.7%(74/213) 32.3% (31/96) 0.56
Cumulative live births, transfer (%)
Fresh cycle 31.2%(124/398) 29.9%(38/127) 30.8%(58/188) 33.7%(28/83) 0.65
Cumulative(fresh cycle+frozen cycle) 29.5%(159/539) 30.5%(54/177) 28.5%(74/260) 30.4%(31/102) 0.77