Table 2. Descriptive synthesis of the included studies comprising the final sample of this integrative review (n=7).
Author, year, country, and language Type of study/sample Objective Main results
Peate et al., 2011
Australia
English
Prospective study
(authors)
n=111
To explore knowledge related to fertility, decisional conflict, preference of information on fertility, and decision-making of female breast cancer patients. Out of 111 participants, 74% wished to receive information about the effects of oncological treatment on fertility.
The lower the knowledge, the higher the decisional conflict on fertility preservation (odds ratio [OR] 0.57; 95% CI, 0.44 to 0.73; p<.001).
Garvelink et al., 2015
Netherlands
English
Qualitative study
(authors)
n=34
To explore the experiences of providing information on gonadotoxic effects, fertility preservation, and the decision-making process of female cancer survivors. The participants report the need for further clarification of fertility preservation procedures and the side-effects of the employed techniques, in addition to alternative options for having children (such as adoption) after chemotherapy.
Srikanthan et al., 2019
Canada
English
Qualitative study
(authors)
n=50
To explore the experiences of breast cancer survivors with fertility during the diagnosis Out of fifty participants, 62% would not submit to fertility preservation treatment unless the available technology offered more than 50% of success probability. For 72%, financial issues limited the search for fertility preservation, even when desired. Clarification of the effects of the treatment on fertility after its conclusion and of other strategies, such as surrogacy and adoption, is required.
Speller et al., 2019a
Canada
English
Qualitative study
n=28
To create and test the “Begin Exploring Fertility Options, Risks, and Expectations” (BEFORE) decision aid for premenopausal breast cancer patients The BEFORE decision aid is an online tool to be used by patients and professionals and applicable to clinical practice (Alpha testing) as a complement to counseling clinical consultations about fertility preservation and decision-making.
Speller et al., 2019b
Canada
English
Qualitative study
(authors)
n=16
To assess six resources/materials aimed at oncofertility decision support for breast cancer patients and health providers The following themes were pointed out by patients and professionals as necessary information to be included in the resources/materials: age and treatment-related fertility decline, post-treatment pregnancy rates made possible by fertility preservation techniques, and the health of children born of surviving patients through fertility preservation techniques.
Ehrbar et al., 2019
Sweden and Germany
English
Randomized
clinical trial
(authors)
n=79
To understand whether the use of an online fertility preservation decision aid in addition to counseling can reduce decisional conflict in fertility preservation The women who received counseling and used the decision aid presented lower decisional conflict compared to the group which received counseling alone (p=0.008; M=12.15, SD=4.38; 95% CI, 3.35-20.95 and p=0.043; M=9.35, SD=4.48; 95% CI, 0.31-18.38).
van den Berg et al., 2021
Netherlands
English
Qualitative study
n=53
To develop and test decision aids for fertility preservation of female cancer patients of reproductive age Survivors and professionals consider decision aids as very useful in the process of decision-making and rated them as 8.5 (1-10 scale). The decision aid must be developed by cancer type and contemplate adoption, surrogacy, and the steps to getting pregnant after cancer treatment.