Table 4

Study	Study design	Karyotype alterations	CFTR variants	SMN1 deletion carriers	FMR1- premutation
Table 4. Comparative results of the frequency of alterations in different studies.
This study	581 female gamete donors	0.9%	1.7%^* 8.1%^†	2.8%	0.2%
Soares et al., 2023	63 female and 34 male gamete donors	1.03%	5.2%^*	2.1%	1.6%
Payne et al., 2021	136 female gamete donors		4.4%^*	0%	1.5%
Zhang et al., 2020	13069 pregnant women			1.77%
Archibald et al., 2018	12000 individuals		2.9%^*	2.0%	0.3%
Urbina et al., 2017	127 females and 16 males		4.2%^*	1.4%	0%
Ben-Shachar et al., 2011	6394 individuals			2.5%

^*Values for the pathogenic CFTR variants;
^ⴕValue for the PolyT 5T allele.