Table 3. List of experimental formulations.
Sr. No. Formulation Uses
1 Intravaginal administration of metformin hydrochloride-loaded cationic niosomes amalgamated with thermosensitive gel It offers analogous advantages as compared to oral metformin hydrochloride (MTF-HCl) solution in the treatment of polycystic ovary syndrome (PCOS) at a lower dosage regimen with probably negligible side-effect (Nowak et al., 2007).
2 Progesterone-loaded nanovesicle transethosomes (NVTES) PRG-loaded NVTEs vaginal gel might be a promising formulation for luteal phase support and increased pregnancy rate in anovulatory PCOS (Wang et al., 2007).
3 Herbal Extracts Loaded Phyto-phospholipid complexes Herbal preparations with low oral bioavailability have a fast first-pass metabolism in the gut and liver. To offset these effects, a method to improve absorption and, as a result, bioavailability must be devised, with antioxidant effects, balances hormones, and anti-inflammatory properties (Choi et al., 2020).
4 Curcumin Encapsulated Self-Assembled Nanoparticles decreasing serum LH, prolactin, testosterone, and insulin levels (Raja et al., 2021).