| Table 2. Demographic data of patients undergoing intracytoplasmic sperm injection | |||||
| Morphokinetic parameter (h) | Winter | Autumn | Spring | Summer | |
|---|---|---|---|---|---|
| n:2,692 | n:1,843 | n:2,801 | n:1,040 | ||
| tPNa | 6.8±0.7a | 6.4±0.8b | 6.8±0.6a | 6.3±0.1b | |
| tPNf | 24.2±1.6 | 24.4±1.2 | 24.2±1.0 | 24.0±1.0 | 0.089 |
| t2 | 26.7±1.7 | 26.9±1.3 | 26.9±1.1 | 26.5±1.1 | 0.059 |
| t3 | 37.4±2.0 | 37.7±1.5 | 37.4±1.3 | 37.2±1.3 | 0.124 |
| t4 | 39.1±2.1 | 39.3±1.5 | 39.2±1.3 | 38.9±1.3 | 0.362 |
| t5 | 49.9±3.0 | 50.0±2.2 | 49.9±1.9 | 49.8±1.9 | 0.943 |
| t6 | 53.0±3.0 | 52.6±2.2 | 52.7±1.9 | 52.8±1.9 | 0.774 |
| t7 | 55.9±3.3 | 55.2±2.4 | 55.6±2.1 | 55.4±2.1 | 0.321 |
| t8 | 59.6±3.8 | 58.7±2.8 | 59.3±2.4 | 58.9±24.1 | 0.190 |
| tM | 90.1±4.2a | 88.6±3.1b | 88.8±2.6b | 88.1±2.5b | |
| tSB | 102.5±4.1a | 100.7±3.0b | 100.9±2.5b | 99.9±2.5c | |
| tB | 111.4±4.8 | 110.2±3.5 | 110.6±2.9 | 110.0±2.8 | 0.08 |
| s1 | 2.3±0.9 | 2.2±0.7 | 2.3±0.6 | 2.2±0.6 | 0.621 |
| s2 | 1.4±0.9 | 1.3±0.7 | 1.3±0.6 | 1.3±0.6 | 0.381 |
| s3 | 7.7±2.6a | 7.1±1.9a,b | 6.8±1.6b | 6.7±1.6b | |
| cc2 | 8.9±1.7a | 8.8±1.3a | 8.2±1.0b | 8.0±1.0b | |
| cc3 | 10.2±2.3a | 10.1±1.7 a | 9.1±1.4 b | 9.5±1.4b | |
| KIDScore | 4.3±0.9a | 4.6±0.7a,b | 4.6±0.6a,b | 4.8±0.6b | |
Note: Values are means±standard errors, unless otherwise noted. H – hours, tPNa – time to pronuclei appearance, tPNf – time to pronuclei fading, t2 – time to two cells, t3 – time to three cells, t4 – time to four cells, t5 – time to five cells, t6 – time to six cells, t7 – time to seven cells, t8 – time to eight cells, tSB – time to start of blastulation, tB – time to blastulation, s1 – time to complete t2-tPNf synchronous divisions, s2 – time to complete t4-t3 synchronous divisions, s3 – time to complete t8-t5 synchronous divisions, cc2 – duration of the second cell cycle (t3-t2), cc3 – duration of third cell cycle (t5-t3). Different subscripts within the same line indicate statistically significant difference. n: Embryos.