| *Table 2. Clinical pregnancy rate and delivery rate in fresh autologous IVF and ICSI cycles stratified according to the age of women in 2021. | |||||||||
| Age of women |
Oocyte retrievals |
Oocyte retrievals* |
Oocyte retrievals** |
Clinical Pregnancies (CPR/OR*) |
Deliveries (DR/OR**) |
PR (95% CI); |
Embryo transfers*** |
Deliveries (DR/ET***) |
PR (95% CI); p-value |
|---|---|---|---|---|---|---|---|---|---|
| ≤30 | 3,825 | 1336 | 1300 | 450 (33.7%) |
352 (27.1%) |
1.00 (Ref.) | 954 | 352 (36.9%) |
1.00 (Ref.) |
| 31-33 | 5,941 | 2381 | 2322 | 756 (31.8%) |
591 (25.5%) |
0.94 (0.84; 1.05); 0.284 | 1,660 | 591 (35.6%) |
0.96 (0.87; 1.07); 0.506 |
| 34-36 | 10,344 | 4429 | 4347 | 1,180 (26.6%) |
928 (21.3%) |
0.79 (0.71; 0.88); <0.001 | 2,905 | 928 (31.9%) |
0.87 (0.78; 0.96); 0.004 |
| 37-39 | 13,787 | 6375 | 6287 | 1,171 (18.4%) |
849 (13.5%) |
0.50 (0.45; 0.56); <0.001 | 3,481 | 849 (24.4%) |
0.66 (0.60; 0.73); <0.001 |
| 40-42 | 13,003 | 6857 | 6805 | 626 (9.1) |
399 (5.9%) |
0.22 (0.19; 0.25); <0.001 | 2,912 | 399 (13.7%) |
0.37 (0.33; 0.42); <0.001 |
| ≥43 | 5,593 | 3476 | 3471 | 136 (3.9%) |
82 (2.4%) |
0.09 (0.07; 0.11); <0.001 | 980 | 82 (8.4%) |
0.23 (0.18; 0.28); <0.001 |
| Total | 52,493 | 24,854 | 24,532 | 4,319 (17.4%) |
3,201 (13.0%) |
- | 12,892 | 3,201 (24.8%) |
- |
After comparing, DR shows no difference between IVF/ICSI we group them together to analyze only the effect of age.* Oocyte retrievals (OR) excludes cases of total embryo freezing.
** OR excluding cases of total embryo freezing and pregnancies with loss to follow-up (LFU).
*** Embryo transfers (ET) excluding pregnancies with LFU.
CPR/OR*: clinical pregnancy rate per oocyte retrieval; DR/OR**: delivery rate per oocyte retrieval excluding LFU; DR/ET***: delivery rate per transfer excluding LFU