| Table 6. Effect of PGT on the delivery rate and miscarriage rate according to age of women in autologous FET and OD FET (2021). | ||||
| Outcome | Age of women | FET with PGT | FET without PGT | Prevalence Ratio (95% CI); |
|---|---|---|---|---|
| Delivery* | Oocyte Donors | 38.3% (375/980) | 33.4% (2,503/7,497) | 0.87 (0.80; 0.95); 0.002¥¥ |
| Autologous <35 |
43.3% (424/980) | 36.4% (2,763/7,587) | 0.84 (0.78; 0.91); <0.001¥¥ | |
| Autologous 35 - 39 |
43.0% (1,005/2,338) | 29.8% (2,948/9,882) | 0.69 (0.66; 0.73); <0.001¥¥ | |
| Autologous >39 |
40.2% (725/1,804) | 21.8% (1,423/6,519) | 0.54 (0.50; 0.58); <0.001¥¥ | |
| Miscarriage* | Oocyte Donors | 18.4% (85/461) | 18.8% (588/3,121) | 1.03 (0.83; 1.26); 0.809¥ |
| Autologous <35 |
14.8% (74/500) | 16.0% (531/3,320) | 1.08 (0.86; 1.35); 0.498¥ | |
| Autologous 35 - 39 |
13.2% (155/1,171) | 20.2% (751/3,720) | 1.52 (1.30; 1.79); <0.001¥ | |
| Autologous >39 |
12.5% (105/837) | 25.0% (482/1,929) | 1.99 (1.64; 2.42); <0.001¥ | |
FET, frozen embryo transfer; OD FET = oocyte donation frozen embryo transfer; PGT, preimplantation genetic testing; Prevalence Ratio. Oocyte donors were <35 years. All analyses were adjusted by women age. Clinical pregnancies with LFU were excluded.
(*) For miscarriage the denominator is clinical pregnancies, for deliveries, the denominator is embryo transfers.}
¥ Likelihood of having a miscarriage. The reference group is “with PGT”.
¥¥Likelihood of delivery. The reference group is “with PGT”.