| Eggert-Kruse et al. (1992) |
Germany |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Voroshilina et al. (2020) |
Russia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Voroshilina et al. (2021) |
Russia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Rivera et al. (2022) |
Colombia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Hillier et al. (1990) |
USA |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Kiessling et al. (2008) |
USA |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Ivanov et al. (2009) |
Russia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Weng et al. (2014) |
Taiwan |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Chen et al. (2018) |
China |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Mändar et al. (2017) |
Estonia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Monteiro et al. (2018) |
Portugal |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Amato et al. (2020) |
Italy |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Baud et al. (2019) |
Switzerland |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Yang et al. (2020) |
China |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Štšepetova et al. (2020) |
Estonia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Motamedifar et al. (2020) |
Iran |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Pochernikov et al. (2020) |
Russia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Okwelogu et al. (2021) |
Nigeria |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Yao et al. (2022) |
China |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Garcia-Segura et al. (2022) |
Spain |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Puerta Suárez et al. (2022) |
Colombia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Koort et al. (2023) |
Estonia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Cao et al. (2023) |
China |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Saldarriaga López et al. (2024) |
Colombia |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Osadchiy et al. (2024) |
USA |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| Vajpeyee et al. (2024) |
India |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
|
|
|
|
|
8/8 |
|
| JBI Critical Appraisal Checklist For randomized controlled trials |
Total |
|
| |
|
Q1 |
Q2 |
Q3 |
Q4 |
Q5 |
Q6 |
Q7 |
Q8 |
Q9 |
Q10 |
Q11 |
Q12 |
Q13 |
X/13 |
|
| Valcarce et al. (2017) |
Spain |
No |
Not applicable |
Yes |
No |
No |
No |
Not applicable |
Yes |
Not applicable |
Yes |
Yes |
Yes |
Yes |
6/13 |
|
| Maretti & Cavallini (2017) |
Italy |
Yes |
Yes |
Yes |
Yes |
No |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
12/13 |
|
| Helli et al. (2022) |
Iran |
Yes |
Yes |
No |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
12/13 |
|
| Abbasi et al. (2021) |
Iran |
Yes |
Yes |
No |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
12/13 |
|
| Grande et al. (2022) |
Italy |
No |
No |
No |
No |
No |
No |
Yes |
Yes |
Not applicable |
Yes |
Yes |
Yes |
Yes |
6/13 |
|
| Asadi et al. (2023) |
Iran |
Yes |
Yes |
Yes |
Yes |
No |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
Yes |
12/13 |
|
| QUIN tool for reviewing risk of bias in vitro studies |
Total |
|
Q1 |
Q2 |
Q3 |
Q4 |
Q5 |
Q6 |
Q7 |
Q8 |
Q9 |
Q10 |
Q11 |
Q12 |
|
X/24 |
% |
| Barbonetti et al. (2011) |
Italy |
2 |
1 |
1 |
2 |
2 |
0 |
1 |
2 |
2 |
1 |
2 |
2 |
18 |
75 |
| Barbonetti et al. (2013) |
Italy |
2 |
1 |
1 |
2 |
2 |
0 |
1 |
2 |
2 |
1 |
2 |
2 |
18 |
75 |
| Raad et al. (2023) |
Lebanon |
2 |
1 |
1 |
2 |
2 |
0 |
1 |
2 |
2 |
1 |
2 |
2 |
18 |
75 |