QUIN tool for reviewing risk of bias in vitro studies
Q1 Clearly stated aims/objectives
Q2 Detailed explanation of sample size calculation
Q3 Detailed explanation of sampling technique
Q4 Details of comparison group
Q5 Detailed explanation of methodology
Q6 Operator details
Q7 Randomization
Q8 Method of measurement of outcome
Q9 Outcome assessor details
Q10 Blinding
Q11 Statistical analysis
Q12 Presentation of results