Table 1. Effect of AEAV at different concentrations and durations on the sperm cells of diabetic human and rat sample in ex vivo study.
Parameters Rat
0 hour 1 hour of incubation 2 hours of incubation
Control group AEAV uncharged diabetes Control group AEAV uncharged diabetes 10 mg AEAV charged diabetes 20 mg AEAV charged diabetes 40 mg AEAV charged diabetes Control group AEAV uncharged diabetes 10 mg AEAV charged diabetes 20 mg AEAV charged diabetes 40 mg AEAV charged diabetes
% of FPMS 52.36±0.78 33.27±0.51b 48.14±0.96c 23.2±0.67d 30.25±0.58e 30.73±0.47e 31.03±0.61e 44.93±0.64f 16.69±0.56s 29.02±0.30e 29.23±0.41e 29.70±0.55e
% of viable sperm 87.28±0.62a 45.68±0.71b 83.41±0.55c 34.50±0.58d 41.44±0.66e 42.23±0.67e 42.65±1.09e 79.05±0.37f 28.75±0.50g 41.47±0.3e 40.77±0.47e 41.96±0.38e
Genomic integrity 76.19±2.65a 43.25±1.18b 71.15±1.69c 32.15±1.24d 39.16±1.26e 39.68±1.37e 40.06±1.64e 66.16±2.33f 21.16±1.65g 38.11±1.02e 39.16±1.09e 39.84±1.22e
Parameters Human
0 hour 1 hour of incubation 2 hours of incubation
Control group AEAV uncharged diabetes Control group AEAV uncharged diabetes 10 mg AEAV charged diabetes 20 mg AEAV charged diabetes 40 mg AEAV charged diabetes Control group AEAV uncharged diabetes 10 mg AEAV charged diabetes 20 mg AEAV charged diabetes 40 mg AEAV charged diabetes
% of FPMS 59.41±1.85a 31.16±2.34b 54.39±1.45c 22.91±1.26d 29.09±0.50e 29.19±0.56e 29.35±0.63e 51.34±1.06f 13.03±0.84g 27.69±0.79e 27.89±0.57e 28.19±0.54e
% of viable sperm 85.91±1.91a 49.33±0.71b 81.16±1.27c 40.96±0.83d 45.23±0.39e 46.11±0.37e 47.55±0.89e 78.55±0.54f 33.78±1.33g 44.68±1.43e 45.35±0.68e 46.31±0.58e
Genomic integrity 71.25±1.24a 41.62±1.21b 67.15±1.25c 30.20±1.39d 36.16±1.26e 36.94±1.35e 37.11±1.21e 63.36±1.38f 20.25±1.68g 35.28±1.57e 36.61±1.25e 37.31±1.36e

Human and rat samples in an ex vivo study. Data represented mean value±SEM, n=16. Mean with different superscripts in every row for rat or human spermiological data vary from one another at significant level, p<0.05. ANOVA followed by posthoc analysis were used as statistical tools and for the significance study.