Table 2. Curative effect of AEAV on oxidative stress and toxicity markers in diabetic rats after 2 hours of exposure to AEAV in an ex vivo condition.
Parameters Control group AEAV uncharged diabetes 10 mg AEAV charged diabetes 20 mg AEAV charged diabetes 40 mg AEAV charged diabetes
Peroxidase activity in liver (unit/mg of tissue) 6.75±1.26a 2.36±0.42b 3.36±0.96c 3.45±0.63c 3.57±0.54c
Peroxidase activity in kidney (unit/mg of tissue) 5.68±0.68a 1.93±0.36b 2.83±0.32c 2.91±0.65c 2.99±0.67c
Peroxidase activity in testis (unit/mg of tissue) 4.63±0.94a 1.06±0.45b 2.21±0.63c 2.25±0.36c 2.26±0.68c
GST activity in liver (µM/min/mg of tissue) 0.751±0.047a 0.233±0.039b 0.301±0.021c 0.306±0.046c 0.311±0.034c
GST activity in kidney (µM/min/mg of tissue) 0.536±0.061a 0.173±0.041b 0.294±0.023c 0.301±0.047c 0.309±0.37c
GST activity in testis (µM/min/mg of tissue) 0.456±0.032a 0.102±0.026b 0.171±0.051c 0.176±0.054c 0.183±0.061c
CD level in liver (unit/mg of tissue) 264.03±3.54a 467.31±4.45b 433.12±4.11c 428.26±4.37c 426.61±3.64c
CD level in kidney (unit/mg of tissue) 197.49±3.64a 378.36±4.21b 357.32±4.26c 353.65±4.31c 349.30±4.95c
CD level in testis (unit/mg of tissue) 159.36±4.01a 329.36±4.34b 301.25±4.65c 296.26±4.63c 293.33±3.44c
Acid phosphatase activity in prostate (mg/PNP/mg of tissue/h) 15.59±2.23a 34.23±1.47b 30.03±1.24c 29.66±1.14c 29.14±1.09c
Alkaline phosphatase activity in prostate (mg/PNP/mg of tissue/h) 12.36±1.19a 31.25 ±1.32b 27.21 ±1.10c 26.68 ±1.53c 26.24±1.38c
AST activity in liver (unit/mg of tissue) 22.32±1.25a 37.15±1.05b 36.14±1.36b 35.60±1.67b 35.15±1.49b
AST activity in kidney(unit/mg of tissue) 16.35±2.71a 34.64±2.37b 33.21±1.25b 32.98±1.54b 32.45±1.23b
ALT activity in liver (unit/mg of tissue) 26.16±3.21a 41.23±3.28b 39.10±2.50b 38.56±1.65b 37.15±1.35b
ALT activity in kidney (unit/mg of tissue) 21.32±2.54a 39.21±2.35b 38.10±1.78b 37.66±1.11b 37.23±1.54b

Data represented mean value±SEM, n=16. Mean with different superscripts in each row vary from one another at significant level, p˂0.05. ANOVA followed by post-hoc analysis were used as statistical tools for the significance study.