Table 2. Exons of male brother to detect MSH5, PLCZ1 mutation sites.
Gene Name	Chromosome location	Nucleic acid changes	Amino acid change	Exon Introns	Heterozygosity	Diseases and genetic patterns	Pathogenicity
MSH5	chr6:g.31727290G	c.1495+1G>T	NA	INTRO	Hybridization	Premature ovarian failure type 13, autosomal recessive inheritance	Suspected to be pathogenic
PLCZ1	chr12:g.18837072A>G	c.1733T>C	p.M578T	Exon 14	Hybridization	Type 17 spermatogenic dysfunction, autosomal recessive inheritance	Clinical significance unclear
PLCZ1	chr12:g.18872463C>G	c.471G>C	p.M157I	Exon 5	Hybridization	Type 17 spermatogenic dysfunction, autosomal recessive inheritance	Clinical significance unclear