Figure 7. Correlations between different glutathione markers in blood and follicular fluid, assessing systemic and local antioxidant capacity. (A) A significant positive correlation between disulfide glutathione (GSSG) and reduced glutathione (GSH) levels in blood, reflecting a functional balance of the redox system. (B) A positive correlation between total glutathione (tGSH) and GSH in blood, highlighting the predominant role of GSH in contributing to the total antioxidant capacity. (C) A significant positive correlation between the GSSG/GSH ratio and GSSG levels in blood, suggesting that an increased oxidative load shifts the redox balance toward a more oxidized state. (D) A significant positive correlation between GSH and GSSG in blood, illustrating an adaptive antioxidant response to oxidative stress. (E) A significant positive correlation between GSH and GSSG in follicular fluid, indicating that the follicular microenvironment mirrors the systemic redox state and endeavors to preserve its local antioxidant equilibrium. r=Spearman’s correlation coefficient. Significant differences are noted when p-value<0.05.