Figure 9
Figure 9. Relationships between the levels of glutathione markers in blood and follicular fluid and the number of oocytes retrieved. (A) A significant negative correlation between the levels of reduced glutathione (GSH) in blood and the number of oocytes retrieved, suggesting that an increase in oocyte retrieval is associated with higher consumption of systemic antioxidants. (B) A significant negative correlation between total glutathione (tGSH) levels in blood and the number of oocytes recovered, indicating the impact of ovarian stimulation on systemic antioxidant capacity. (C) A significant positive correlation between disulfide glutathione (GSSG) levels in follicular fluid and the number of oocytes retrieved, reflecting intensified local metabolic activity and an increase in the generation of reactive oxygen species (ROS) in the follicular environment with the increase in the number of oocytes obtained. r=Spearman’s correlation coefficient. Significant differences are noted when p-value<0.05.