| Table 1. Summary of published cases of ex vivo oocyte retrieval following ovarian stimulation in patients with ovarian tumors. | ||||||||
| Reference | Age | Marital Status / Parity / Clinical History | COS Protocol | Type of Surgery | Pathology | Ultrasound-Guided Retrieval | Oocytes Retrieved | Oocytes Matured In Vitro |
|---|---|---|---|---|---|---|---|---|
| 27 | Not reported; nulligravid; previous laparoscopic left salpingo-oophorectomy; recurrent serous papillary adenocarcinoma | rFSH 200 IU/day; ganirelix 0.25mg/day from day 6; trigger with urinary hCG 10,000IU | Laparotomy | Recurrent serous papillary adenocarcinoma | No | 13 | 0 | |
| 25 | Single; nulligravid; previous laparoscopic salpingo-oophorectomy; serous borderline tumor | rFSH 200 IU/day; ganirelix 0.25mg/day from day 7 to 10; trigger with rhCG 250µg on day 10 | Laparoscopy (~34-35h after trigger) | Serous borderline tumor | No | 14 | 0 | |
| 37 | Single; nulligravid; AFC ~14 | rFSH 300IU/day + hphMG 150IU/day + letrozole; then rFSH 150IU/day; ganirelix 0.25 mg/day; trigger with rhCG 250 µg on day 12 | Laparotomy (~34h after trigger) | Not reported | No | 7 | 0 | |
| de la Blanca et al . ( |
31 | Single; nulligravid; previous left salpingo-oophorectomy; mature teratoma; AMH 1.1 ng/mL | Corifollitropin alfa 150 µg; rFSH 200IU/day; ganirelix 0.25 mg/day; trigger with rhCG 250 µg on day 10 | Laparoscopy (~35 hafter trigger) | Struma ovarii | Yes | 5 | 0 |
| Rezacova et al . ( |
34 | Single; nulligravid; no family history of cancer; micropapillary serous BOT; AMH 3.91 ng/mL | recFSH (Puregon 175IU/day); Cetrotide from day 6; Ovitrelle on day 11 | Laparotomy (~35h after trigger) | Micropapillary serous borderline tumor | No | 10 | 9 |
| de Carvalho et al . (2021) |
28 | Married; nulligravid; bilateral serous BOT; elevated CA-125; risk of dissemination | Corifollitropin alfa 150 µg + rFSH 250IU/day + ganirelix; trigger with triptorelin | Laparoscopy (~37h after trigger) | Bilateral serous borderline tumor with microinvasion | Yes | 16 | 3 |