Table 1. Impact of a high-fat diet (HFD) on body weight, and serum lipid profile in adult Swiss albino mice after 12 weeks of feeding.
Parameter Groups Significance
(p-value)
Control Obese
Gain in body weight (g) 14.84±0.89 (n=41) 20.38±0.89 (n=43) p<0.001
HDL cholesterol (mg/dL) 434.30±32.50 (n=11) 608.50±43.24 (n=9) p<0.01
LDL cholesterol (mg/dL) 18.84±1.45 (n=11) 52.08±3.01 (n=9) p<0.001
Total cholesterol (mg/dL) 58.63±5.22 (n=11) 93.00±9.03 (n=9) p<0.01

Data are presented as mean ± SEM. HDL - high-density lipoprotein; LDL - low-density lipoprotein. “n” represents the number of animals used.