| Table 1. MR Analysis of exposures and Gut Microbiota: Heterogeneity, Pleiotropy, and MR-PRESSO Results. | |||||
| Exposure | microbiota | Heterogeneity(pval) | Pleiotropy(pval) | MR-PRESSO(pval) | |
|---|---|---|---|---|---|
| MR Egger | IVW | ||||
| GCST90032179 | Actinobacteria | 0.140 | 0.175 | 0.675 | 0.165 |
| GCST90032181 | Actinomycetales | 0.500 | 0.586 | 0.952 | 0.569 |
| GCST90032219 | Bifidobacteriaceae | 0.238 | 0.281 | 0.665 | 0.256 |
| GCST90032230 | Bifidobacterium | 0.407 | 0.433 | 0.434 | 0.417 |
| GCST90032304 | CAG-841 sp002479075 | 0.592 | 0.467 | 0.141 | 0.524 |
| GCST90032413 | GCA-900199385 sp900320755 | 0.515 | 0.586 | 0.869 | 0.605 |
| GCST90032522 | Prevotella sp002933775 | 0.247 | 0.300 | 0.715 | 0.335 |