| Table 3. Secondary outcomes: A. Obstetric outcomes in the PGT and non-PGT groups, B. Live birth rate based on PGT characteristics. | |||
| A. Obstetric outcomes | |||
|---|---|---|---|
| PGT (n=97) | Non-PGT (n=99) | p-value | |
| Pregnancy outcome Clinical pregnancy Chemical pregnancy Extrauterine pregnancy |
92/97 (95%) 5/97 (5%) 0 (0) |
94/99 (95%) 5/99 (5%) 3/99 (3%) |
NS NS NS |
| IUFD | 2/97 (2%) | 3/99 (3%) | NS |
| Miscarriage | 19/97 (19%) | 13/99 (13%) | NS |
| Live birth All cycle Fresh cycles Frozen-thawed cycles |
71/97 (73%) 24/29 (82%) 47/68 (69%) |
75/99 (75%) 23/27 (85%) 52/72 (72%) |
NS |
| Mode of delivery Vaginal delivery Cesarean section |
60/72 (83.4%) 12/72 (16.6%) |
60/76 (78.9) 16/76 (21.1) |
NS |
| Gestational age at delivery (weeks) | 39±1 | 38+6±3.0 | NS |
| Birth weight (grams) | 3199.5±556.5 | 3204.6±527 | NS |
| B. Live birth in the PGT group | ||
|---|---|---|
| Live birth (n=72) | p-value | |
| Biopsy day Day 3 Day 5 |
48/63 (76.1%) 24/34 (70.5%) |
NS |
| Type of PGT PGT-A PGT-M PGT A+M |
13/18 (72.2%) 54/74 (72.9%) 4/5 (80%) |
NS |
| Mutation carrier Maternal Paternal Both |
25/36(69.4%) 20/27 (74.1%) 6/9 (66.7%) |
NS |
| Number of mutations 1 2 3 |
66/87 (75.9%) 5/9 (55.6%) 0/1 |
NS |
| Infertility type Primary infertility Secondary infertility |
4/8 (50%) 1/4 (25%) |
NS |
| Blastocyst grade Good Fair Poor |
45/60 (75%) 21/30 (70%) 3/6 (50%) |
NS |
IUFD = intrauterine fetal death, NS = not significant, PGT-A = preimplantation genetic testing for aneuploidy, PGT-M = preimplantation genetic testing for monogenic disorders.