Figure 1. Effects of Repeated Ovarian Hyperstimulation on Body Weight in Female Mice. (A) Experimental design of repeated ovarian hyperstimulation in female mice. The treated group received 7.5 IU of human menopausal gonadotropin (HMG) once per week (on Tuesdays) followed by 5.0 IU of human chorionic gonadotropin (hCG) 48 hours later (on Thursdays) for 10 weeks. The placebo group received saline solution at equivalent time points. (B) Body weight progression of treated and control groups during the 10-week protocol. Data are presented as mean±SEM, with significant differences between groups marked as follows: *p<0.05, **p<0.01, ***p<0.001, and ns for not significant. Treated mice exhibited a significant increase in body weight compared to controls starting from the second week.