Table 3. Effect of ATRA on spermatogenesis indices in the ipsilateral testis following TD
Groups Spermatogonia Spermatocyte Spermatid Sertoli Leydig
Sham 59.00±0.41 77.75±0.85 58.00±0.82 16.75±0.48 198±1.11
TD 1.500±0.96a 3.750±2.18a 3.250±1.89a 3.250±0.25a 33.25±0.95a
ATRA+TD 40.00±4.98b 56.25±6.29b 44.00±3.24b 13.75±1.315b 169.0±4.00b
TD+ATRA 4.250±1.89c 5.500±3.202c 5.000±2.92c 2.750±0.250c 27.00±0.707c

Data are presented as mean±SEM (n=6).
Spermatogonia count: a significant decrease (p<0.001) compared with the sham group; b significant increase (p<0.001) compared with the TD group; c significant decrease (p<0.001) compared with the ATRA+TD group.
Spermatocyte count: a significant decrease (p<0.001) compared with the sham group; b significant increase (p<0.001) compared with the TD group; c significant decrease (p<0.001) compared with the ATRA+TD group.
Spermatid count: a significant decrease (p<0.001) compared with the sham group; b significant increase (p<0.001) com-pared with the TD group; c significant decrease (p<0.001) compared with the ATRA+TD group.
Sertoli cell count: a significant decrease (p<0.001) compared with the sham group; b significant increase (p<0.001) com-pared with the TD group; c significant decrease (p<0.001) compared with the ATRA+TD group.
Leydig cell count: a significant decrease (p<0.001) compared with the sham group; b significant increase (p<0.001) com-pared with the TD group; c significant decrease (p<0.001) compared with the ATRA+TD group.