Table 4. Comparison of reproductive outcomes in patients aged ≥41 years
Variable Double Trigger (n=15) r-hCG (n=13) p-value
Fertilization rate 75.0 (63.3-100.0) 50.0 (33.3-75.0) 0.073
Cleavage rate 66.7 (45.0-95.2) 33.3 (0.0-75.0) 0.162
Blastulation rate 0.0 (0.0-22.6) 0.0 (0.0-0.0) 0.095
2PN-fertilized oocytes 3.0 (2.0-5.0) 2.0 (1.0-2.0) 0.034
D3 embryos 2.0 (2.0-4.0) 2.0 (0.0-2.0) 0.025
D5 embryos 0.0 (0.0-2.0) 0.0 (0.0-0.0) 0.082

Values are expressed as median (interquartile range). Fertilized 2PN oocytes, fertilization, cleavage, and blastulation rates, as well as the number of embryos on day 3 (D3) and day 5 (D5) were compared between the Double trigger and r-hCG groups. p-values are from Mann–Whitney U tests and are reported for descriptive/exploratory purposes due to skewed distributions and small subgroup sizes. A p<0.05 was considered significant.