JBRA Assisted Reproduction 2025;29(Suppl.2 SBRA 2025):48
Poster Presentation
29^th Annual Congress of the SBRA. São Paulo/SP - Brazil, 2025
doi: 10.5935/1518-0557.20263587

P-36. Body Mass Index of Oocyte Recipients Does Not Impact Ongoing Pregnancy Rates After Transfer Of Good-Quality Blastocysts

Rogerio de Barros Ferreira Leão¹, Arnaldo Schizzi Cambiaghi¹, Paula Bortolai Martins Araújo¹, Thais de Grande Cambiaghi¹, Michaele Xavier Amaral¹, Nathalia Uzun Troiano¹, Helena Mura Santos¹

¹IPGO - São Paulo - SP - Brasil

Objective: To evaluate whether the body mass index (BMI) of oocyte recipients influences reproductive outcomes in cycles of blastocyst transfer when at least one transferred embryo had good quality (≥3BB).
Methods: This retrospective study included 423 embryo transfers performed between January 2021 and April 2025. All oocyte donors were younger than 32 years. Inclusion criterion was transfer in which at least one blastocyst had a quality grade ≥3BB on day 5 or day 6. Recipients were classified according to BMI (underweight <18.5; normal 18.5–24.9; overweight 25–29.9; obese ≥30). Outcomes analyzed were pregnancy rate, clinical pregnancy rate, miscarriage rate, and ongoing pregnancy rate. Group comparisons were performed using the chi-square test, and logistic regression assessed the association between BMI and outcomes.
Results: Among the 423 transfers, 14 (3.3%) were underweight, 237 (56.0%) normal weight, 130 (30.7%) overweight, and 42 (9.9%) obese. Ongoing pregnancy rates were 50.0%, 58.6%, 53.1%, and 54.8%, respectively, with no statistically significant differences. Logistic regression showed no association between BMI and ongoing pregnancy. The odds ratio per unit increase in BMI was 0.98 (95% CI: 0.94–1.03; p=0.51). Similarly, pregnancy rates (78.6%, 78.1%, 70.0%, 66.7%), clinical pregnancy rates (50.0%, 62.0%, 56.2%, 57.1%), and miscarriage rates (18.2%, 24.6%, 21.2%, 17.9%) showed no significant differences across groups.
Conclusion: In oocyte recipients undergoing transfer of good-quality embryos, BMI did not influence pregnancy, clinical pregnancy, miscarriage, or ongoing pregnancy rates, suggesting no impact of BMI on immediate reproductive outcomes. However, this finding does not invalidate the well-established risks of excess or deficient weight for obstetric and perinatal complications, which remain relevant in the clinical management of these patients and were not assessed in this study.