| Table 5. Embryo transfer characteristics and pregnancy outcomes in IVF patients in the PURO study. | ||
| Outcome | n | % |
|---|---|---|
| Patients undergoing IVF |
1448 | - |
| Preimplantation genetic testing | n | % |
| Total | 944 | 65.2 |
| PGT-A | 913 | 63.1 |
| PGT-M | 15 | 1.0 |
| PGT-SR | 16 | 1.1 |
| Cycles without PGT | 504 | 34.8 |
| Patients without transfer - cycle cancellation (poor response) + no oocytes/embryos available Cycle cancellation: No oocytes: No MII oocytes: No blastocysts: No euploid blastocysts: Total: |
81 19 18 190 265 573 |
5.6 1.3 1.2 13.1 18.3 39.6 |
| Patients without transfer - personal reasons |
160 | 11 |
| Patients not lost to personal-reason dropout | 1288 | |
| Patients with embryo transfer | 715 | 49.4 |
| Frozen embryo transfer (first) | 617 | 86.3 |
| Fresh embryo transfer (first) | 98 | 13.7 |
| D5 transfers |
688 | 96.2 |
| D3 transfers |
27 | 3.8 |
| Single embryo transfer | 587 | 82.1 |
| Double embryo transfer | 120 | 16.8 |
| Triple embryo transfer | 8 | 1.1 |
| Biochemical pregnancy rate (β-hCG+) |
445 | 62.2 |
| Ongoing pregnancy rate per transfer after 1st embryo transfer | 360 | 50.3 |
| Ongoing pregnancy rate per initiated cycle |
360/1288 | 27.9% |
| Ongoing pregnancy rate |
81/191 | 42.4% |
| Ongoing pregnancy rate |
12/49 | 24.5% |
| Ongoing pregnancy rate |
9/16 | 56.3% |
| Mean number of transfers/patient | 1.4 (971/715) | |
*Data are presented as numbers (percentage).
1 IVF = in vitro fertilization
2 Patients without transfer – personal reasons: patients who had embryo(s) available for transfer but did not return to undergo embryo
transfer before the end of the study’s data collection period.
3 D5 = day 5 embryo transfer
4 D3 = day 3 embryo transfer
5 β-hCG = beta human chorionic gonadotropin.
6 Ongoing pregnancy was defined as a detectable fetal heartbeat beyond 12 completed weeks of gestation