| Table 2. Cycle characteristics and laboratory outcomes according to stimulation protocol and overall oocyte cryopreservation cohort (n = 705). | ||||||
| Variable | Protocol 1 Algorithm (n=17) |
Protocol 2 Empirical monotherapy (n=130) |
Protocol 3 Mixed HMG (n=494) |
Protocol 4 Mixed FSHr+LHr (n=44) |
Protocol 5 Others (n=20) |
Oocyte Cryopreservation overall (n=705) |
|---|---|---|---|---|---|---|
| Age (years) | 34.8±3.5 | 35.0±3.9 | 35.7±3.6 | 36.5±4.0 | 35.6±5.1 | 35.6±3.7 |
| Weight (kg) | 62.8±7.3 | 63.5±11.0 | 63.0±9.9 | 62.3±7.8 | 66.9±10.5 | 63.3±10.1 |
| Partner age (years) | - | 42.5±9.3 | 41.3±9.0 | 39.0 | 40.0±7.1 | - |
| AMH (ng/mL) | 4.0±2.0 (n=17) | 3.3±2.6 (n=99) | 1.9±1.9 (n=397) | 2.0±2.1 (n=34) | 3.4±3.3 (n=13) | 2.3±2.2(n=559) |
| AFC | 19.7±7.8 | 16.4±9.1 | 12.2±7.1 | 14.1±7.9 | 13.5±9.1 | 13.4±7.9 |
| Duration of stimulation (days) | 9.3±1.2 | 9.8±1.4 | 10.0±1.7 | 10.8±1.8 | 11.5±2.8 | 10.0±1.7 |
| Oocytes retrieved (n) | 15.3±7.8 | 14.8±10.0 | 12.4±8.9 | 11.5±8.4 | 15.1±10.7 | 12.9±9.2 |
| MII oocytes (n) | 11.9±6.0 | 11.2±7.9 | 9.2±6.9 | 8.4±6.3 | 10.2±7.2 | 9.7±7.1 |
Data are presented as mean±standard deviation (SD).
Protocol 1 (algorithm)
Protocol 2 (non-algorithm monotherapy)
Protocol 3 (delta + hMG)
Protocol 4 (delta + rFSH/LH)
Protocol 5 (others)
AMH = anti-Müllerian hormone
AFC = antral follicle count
MII = metaphase II oocytes
2PN = two pronuclei