| Table 1. Live birth outcomes in real-world studies comparing PGT-A and non-PGT-A cycles | |||||
| Study | Outcome denominator | LBR Control (%) (n/N) | LBR PGT-A (%)
|
Odds ratio (95% CI) | Direction of effect |
|---|---|---|---|---|---|
| SART (2022) | ET | 41% (19,398/47,238) | 53% (51,264/96,855) | 0.61 (0.60-0.62) | Favors PGT-A |
| Zegers-Hochschild
|
ET | 34% (9,245/26,870) | 41% (6,589/16,101) | 0.75 (0.72-0.78) | Favors PGT-A |
| Sarkar
|
ET | 43% (3,043/7,128) | 49% (4,410/9,014) | 0.78 (0.73-0.82) | Favors PGT-A |
| Ma
|
CI/OR | 31% (3,150/10,140) | 22% (1,155/5,350) | 1.64 (1.51-1.70) | Favors Control |
| Roberts
|
CI/OR | 44% (19,476/44,656) | 27% (809/3,001) | 2.10 (1.92-2.27) | Favors Control |
| Zegers-Hochschild
|
CI/OR | 24% (9,245/38,572) | 17% (6,589/38,381) | 1.52 (1.47-1.57) | Favors Control |
SART: Society for Assisted Reproductive Technology
RedLARA: Latin American Network of Assisted Reproduction
LBR: live birth rate
ET: embryo transfer
CI: cycle initiated
OR: oocyte retrieval.