Table 1. Ovarian stimulation and IVF results in patients | ||||
Groups |
Normal weight (n = 2222) |
Overweight (n = 379) |
Obesity (n = 27) |
p value |
Cycle cancellation | 205 (9.2%) | 22 (5.8%) | 1 (3.7%) | > 0.05 |
Days of stimulation | 10.42 ± 2.03 | 10.60 ± 2.16 | 11.89 ± 4.57* | < 0.001 |
Gn dose (IU) | 2,587 ± 933 | 2,688 ± 966** | 3272 ± 1798* | < 0.001*, < 0.05** |
Peak E2 (pmol/L) | 13,757 ± 10,212 | 11,307 ± 8,999 | 10290 ± 9048 | > 0.05 |
Oocytes retrieved | 14.49 ± 7.96 | 12.98 ± 6.91* | 12.48 ± 5.89 | < 0.001 |
Fertilised eggs | 8.87 ± 5.96 | 7.72 ± 4.85* | 6.78 ± 4.16 | < 0.001 |
Fertilisation rate (%) | 61.1 ± 23.0 | 60.8 ± 23.3* | 54.1 ± 21.3* | < 0.001 |
Cleavaged embryos | 8.67 ± 5.90 | 7.55 ± 4.86* | 6.96 ± 4.25 | < 0.001 |
High-grade embryos | 5.59 ± 4.81 | 4.65 ± 3.96* | 4.56 ± 2.94 | < 0.001 |
Cryopreserved embryos | 5.49 ± 5.55 | 4.44 ± 4.55* | 3.81 ± 4.01 | < 0.001 |
Numbers of embryos tranferred | 2.15 ± 0.90 | 2.30 ± 0.84 | 2.19 ± 0.68 | > 0.05 |
Continuous data were analysed using one-way ANOVA test, and post-hoc comparisons were performed using the LSD test. Chi-square test was used to assess the categorical variables. *p < 0.001, compared with the normal weight group. **p < 0.05, compared with the normal weight group. Adapted from Zhang et al., 2010. |