Table 1. Selected KPIs with high agreement according to the ESHRE consensus documents (Vaiarelli et al., 2023; Latif Khan et al., 2023).
Key performance indicators				Competence value	Benchmark value	Frequency of analysis
Structural KPIs	Staff-to-Cycle Ratio				150 cycles-2 embryologists 151to 300 cycles-3 embryologist 300 to 600-4-5 embryologists >600 cycles- 1 embryologist for 200 cycles	annually
	Lab Space per Workstation				≥10-12 m2 per workstation	During setup and annually
	Lab environment	Fresh air			20%	Continuous
		Temperature			24 to 26°C
		Humidity			40-60%
		Positive pressure			>+30 Pa
		Particle count			< 10,000 particles (> 0.5µm to 10 µm/cubic foot of air)
		Microorganisms			5 colonies/90 mm Petri plate in passive samples
Process KPIs	Fertilization rate	IVF		60%	75%	Monthly or 100 cycles
		ICSI (includes only fresh or frozen spermatozoa		65%	80%	Monthly or 100 cycles
	IVF failed fertilization rate				5%	Monthly or 100 cycles
	ICSI damage rate			10%	5%	Monthly or 100 cycles
	Fertilized oocyte cleavage rate			>95%	>99%	Monthly or 100 cycles
	Blastocyst development rate (Day 5)			40%	60%	Monthly or 100 cycles
	Good Quality Blastocyst Development Rate			30%	40%	Monthly or 100 cycles
	Cycle cancellation rate before oocyte pick-up			≤30% (poor responders) ≤ 3% (normal or hyper responders)	≤10% (poor responders) ≤ 0.5% (normal or hyper responders)	3 months or 100 cycles
Outcome kPIs	Clinical pregnancy rate 35-39 years >40 years		≤ 34 years	≥ 30%	≥ 40%	3 months or 100 cycles
			≥ 20%	≥ 30%
			≥ 10%	≥ 20%
	Multiple pregnancy rate			≤ 10%	≤ 5%	3 months or 100 cycles
	Rate of cycles with moderate to severe OHSS			≤ 3%	≤ 0.5%	6 months or 100 cycles
	Miscarriage rate 35-39 years >40 years		≤ 34 years	≤ 20%	≤ 15%	6 months or 100 cycles
			≤ 35%	≤ 25%
			≤ 50%	≤ 40%