Table 3. GnRH antagonist versus GnRH-a (long protocol and fl are-up) : number of mature oocyte
Trail GnRHantagonist mean±sd GnRHagonist mean±sd Mean diff 95% CIfixed
Long protocol
Cheunget al., 2005 19 5.32±2.73 21 5.0±3.26 0.32 (-1.55, 2.19)
D’Amato Et al., 2004 81 4.29±0.95 40 2.65±1.12 1.64 (1.25, 2.02)
Fixed effects (Mulrow-Oxman) Pooled effect size Z (teste WMD + differs from 0) = 7.84 p<0.0001Non-combinability / Cohran Q = 1.85 (df =1) p = 0.17 WMD = 1.58 (1.18 to 1.97)
Flare-up
Akmanet al., 2001 20 4.0±1.8 20 4.5±1.9 -0.5 (-1.65, 0.65)
Malmusiet al., 2005 18 1.7±1.2 24 3.2±1.5 -1.5 (-2.34,-0.65)
Schmidtet al., 2005 13 7.7±0.9 11 6.5±1.1 1.2 (0.40,1.99)
Fixed effects (Mulrow-Oxman) Pooled effect size Z (teste WMD + differs from 0) = -0.82 p = 0.41Non-combinability / Cohran Q = 21.36 (df =2) p < 0.0001 WMD = -0.216 (-0.73 to 0.30)