Table 4. GnRH antagonist versus GnRH-a (long protocol and fl are-up) : clinical pregnancy rate per cycle initiated
Trial GnRHantagonist GnRHagonist %Weights Odds ratio 95% CI
Long protocol
Cheunget al., 2005 5/31 3/32 25.5 1.85 (0.32, 13)
Marciet al., 2005 5/30 2/30 17.2 2.8 (0.40, 31.3)
D’Amato et al., 2004 18/85 6/60 57.2 2.41 (0.83, 7.9)
Pooled odds ratio = 2.34 (1.10 to 4.94)Fixed effects (Mantel-Haenszel, Robins-Breslow-Greenland) Chi2 (test odds ratio differs from 1) = 4.36 p = 0.0367Non-combinability of studiesBreslow-Day = 0.133 (df=2) p = 0.9355 Cochran Q = 0.13 (df=2) p = 0.9356