Figure 2. (A) Normal spermatozoa, (B-C); Abnormality of nuclear form: spermatozoa with small or large oval nuclear forms (B); spermatozoa with wide or narrow nuclear forms (C); (D-F) Abnormalities in nuclear chromatin: spermatozoa with regional shape abnormality of nuclear form (D), spermatozoa with vacuoles occupying 5-50% of the nuclear area (E) spermatozoa with large nuclear vacuoles (>50% of the nuclear area) (F)..