Marcia E Garcez, Cátia dos Santos Branco, Luana V Lara, Patricia D S Spada, Fabio F Pasqualotto, Mirian Salvador
JBRA Assist. Reprod. 2011; 15 (6):15-16
Received August 08, 2011
Accepted August 30, 2011
Abstract
The aim of this study was to analyze potential beneficial effects of adding ascorbic acid to cryopreservation media of semen of infertile men. Semen from 20 infertile and 10 fertile (control group) men was cryopreserved with and without 10 mM ascorbic acid. Addition of ascorbic acid to the cryopreservation media was able to reduce the lipid oxidative damage induced by the cryopreservation process and increase the antioxidant enzyme superoxide dismutase activity in infertile men. However, this antioxidant was not able to avoid the loss of motility observed in post-thaw spermatozoa of both infertile and fertile men.
