Nilo Frantz, Marcelo Ferreira, Gerta Frantz, Marcos Höher, Norma Oliveira, Talita Giacomet de Carvalho, Adriana Bos-Mikich
JBRA Assist. Reprod. 2010; 14 (2):24-26
Received April 14, 2010
Accepted July 18, 2010
Abstract
Objective: The in vitro maturation (IVM) of oocytes collected in unstimulated cycles is an attractive alternative to classic assisted reproduction (AR) treatments. The procedure is particularly indicated for patient with polycystic ovaries (PCO) or polycystic ovaries syndrome (PCOS). The present study reports our experience with 34 cycles of IVM applied to PCO (n=7) or PCOS (n=27) patients.
Methods: Cumulus-oocyte complexes were collected 36h post-hCG in unstimulated cycles. After in vitro maturation for 28 to 30 hours, oocytes that reached
MII were inseminated by ICSI. Embryos were transferred on day-3.
Results: In the present series of IVM cycles, we obtained an average of 16.3 oocytes collected per cycle, 63% and 62% of in vitro maturation and fertilization,
respectively. We obtained a clinical pregnancy rate of 32% (11/34). Conclusion: The IVM methodology combines several advantages, such as the absence of hyperstimulation, low costs and easiness to monitor the cycle. We believe that IVM represents a valid choice of infertility treatment for a specific group of patients.
