ISSN 1518 0557
Predictors of Pregnancy after Artificial Insemination in Women with Polycystic Ovary Syndrome

2025; 29
Tânia Moreira, Carla Leal, Márcia Barreiro, Antônio Tomé, Emídio Vale-Fernandes
JBRA Assist. Reprod. 2025; 29 (2):201-210

Received May 20, 2024
Accepted November 25, 2024
Abstract

Objective: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, being one of the main causes of infertility. Anti-M�llerian hormone (AMH) is an important marker of ovarian reserve and has been proposed as an alternative criterion for the diagnosis of PCOS. This study verifies whether AMH and BMI values are predictors of pregnancy in infertile women with PCOS undergoing artificial insemination (AI), a less invasive and painless technique of assisted reproductive technologies (ART). Methods: This retrospective observational study involved 220 women with PCOS who underwent AI between 2010 and 2022. Participants were categorized into three groups based on BMI and serum AMH levels. To categorize the three AMH classes, the 25th (4.08ng/mL) and 75th (8.99ng/mL) AMH percentiles were defined as cut-offs, and the words 'low', 'middle', and 'high' were utilized to define the groups. Results: There was a tendency towards a decrease in reproductive outcomes (number of inseminations with positive human-chorionic gonadotropin, number of live births, and number of term births) with an increase in the BMI value. All of these outcomes were also slightly higher in women with 'middle' AMH levels compared to women with 'low' and 'high' AMH. However, none of these results were statistically significant. Conclusion: This study shows BMI is an important predictive factor for pregnancy and there appears to be a range of biological normality for AMH values, where 'low' and 'high' levels of this hormone could constitute a marker of poor reproductive prognosis, in women with PCOS undergoing AI.


This Article

doi: 10.5935/1518-0557.20240095

Full Text (HTML)
Full Text (PDF)

Classifications

Original article

Send this article

Send this article by mail

Access statistics

Last 30 days: 85
All time: 2343


Home

 
Copyright 2026 - JBRA Assisted Reproduction - All rights reserved.
Support and Maintenance by Eniosoft