Received May 27, 2019
Accepted December 10, 2019

Objective: To study the value of oxygen consumption (OC) as a predictor of the developmental potential of D3 embryos in frozen embryo transfer (FET) cycles. Methods: This observational study included 148 pa- tients undergoing FET cycles with two embryos transferred per cycle. OC rates were examined by scanning electro- chemical microscopy before embryo transfer. Implantation, clinical pregnancy, miscarriage, and live birth rates were calculated. Results: A total of 296 embryos were transferred in 148 cycles, or two embryos per cycle. The embryos were divided into three groups based on OC: Group A included the cases in which the OC rate of each of the two trans- ferred embryos was greater than 3.0 fmol/s; Group B in- cluded the cases in which the OC rate of one of the embry- os was greater than 3.0 fmol/s and the OC rate of the other embryo was less than 3.0 fmol/s; and Group C included the cases in which the OC rates of the two embryos were less than 3.0 fmol/s. Higher live birth rates and lower miscar- riage rates were observed in Group A (p<0.05). Conclusions: Our data suggest that OC is positively correlated with embryo developmental potential. There- fore, measuring the OC of human embryos may be useful in embryo assessment.